Your both paths are referring in wrong way,
mysite urls.py
from django.contrib import admin
from django.urls import include, path
urlpatterns = [
path('', include('AppTwo.urls')),
path('admin/', admin.site.urls),
]
AppTwo urls.py,
from django.urls import path
from . import views
urlpatterns = [
path('help/', views.help, name='help'),
path('users/', views.users, name='users'),
]
In your question, you are adding different paths to include same app i.e. AppTwo.urls, which means your app two urls will start with either 127.0.0.1:8000/help/ or 127.0.0.1:8000/users/ and as in the app urls the path is blank so in both cases both views will refer to same path. Hence the url will fail.
In your project include your app.urls once and then in your app urls.py show the path for the views.