PEP 8 and the Google Python Style Guide differ in several aspects of code formatting and conventions. Regarding indentation, PEP 8 recommends using 4 spaces, while the Google Python Style Guide suggests 2 spaces. Line length is another area of distinction, with PEP 8 advocating for a maximum of 79 characters per line, while the Google Python Style Guide allows up to 100 characters. Naming conventions also vary slightly, as PEP 8 suggests lowercase with underscores for variables and functions (snake_case), whereas the Google Python Style Guide permits lowercase with underscores or lowercase with initial uppercase letters for variables (lower_case or lowerCamelCase) and lowercase with underscores for functions. Import statements follow different practices, with PEP 8 advising each import on a separate line, while the Google Python Style Guide allows multiple imports on a single line if they share the same source. Comments and documentation guidelines also diverge, as PEP 8 encourages limited use of inline comments, while the Google Python Style Guide emphasizes effective comments for clarity and provides specific instructions for documenting functions, classes, and modules using docstrings. Error handling practices vary as well, with the Google Python Style Guide promoting the use of specific exception classes whenever possible, while PEP 8 is more flexible in this regard. Finally, regarding blank lines, PEP 8 recommends minimal usage within functions and classes, whereas the Google Python Style Guide suggests employing more blank lines for improved readability and logical separation. Ultimately, the choice between adhering to PEP 8 or the Google Python Style Guide depends on personal preference or the specific style guide adopted within an organization or development team.